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                        Why does skin age?

When you are young, your skin is thick and elastic-high in Collagen and Elastin  fibers. As one grows older, the body slows down the production of the essential ingredients it requires to maintain its youthful appearance and elasticity. As a result, the skin becomes thinner and more susceptible to wrinkles, sagging skin, bruising and tearing of the outer layer.

Aging is a fact of life, photo aging id that damage done to the skin due to the direct effects of ultraviolet light. clinically the person will present with skin that has sallow complexion, with surface mottling, and a coarse thickened texture. The skin will often sag or droop due to loss of integrity of the elastic tissue. Wrinkles will be major cosmetic concern, brown spotting (solar lentigines), telangiectasia as well as actinic and seborrheic keratosis.

Solar elastosis ( clinical photoaging) consists of deposition of massive amounts of abnormal elastic material, in the upper reticular dermis. The abnormal elastic fibers being deposited are accompanied by massive amounts of chondroitin sulfate molecules ( versican). This increase in versican and abnormal elastic fibers are accompanied by a corresponding decrease in amounts of collagen and a collagen associated proteoglycan.

What the mechanism of formation of solar elastosis? the primary mutagen seems to be ultraviolet light, exposure to ultraviolet light type A (UVA 320-360 nanometers) led to an increase in free radicals which in turn led to an up regulation and synthesis of interstitial collagenase which would increase collagen degradation and connective tissue damage.

What is available to help combat these forces of ageing? 

1- First and foremost, use of sunscreen.

2- Second, AHA ( Alpha Hydroxy Acid ) is another rejuvenating agent frequently used by cosmetic surgeons and dermatologists. Histologically, alpha hydroxy acid, have been shown to increase the thickness of the epidermis, as well as cause increased collagen density, improve elastic fiber quality, increase papillary dermal thickness and increase dermal acid mucopolysachharides, translating clinically into thicker, healthier skin. To obtain both ingredients, the Tretinoin and the AHA check our Doctor Twaian Power Re-New

                       

                                           

              

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MediDerm Laboratories, LLC
 
Headquarter : 41571 Corning Place, Suite 105
                        Murrieta, CA 92562
           Phone # 310-312-4570   Fax # 714-242-1609
 
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